FFPE tissue sounds like its super complicated. But it’s not, its just a method of storing tissue samples. Being able to store tissue samples for long periods of time without compromising its integrity is crucial to disease research and thats why FFPE is so popular.
FFPE allows the extraction of high quality nucleic acids and can be widely used for genomic biomarker discovery studies. A big part of biomarker research in tissue is centered on cancer. Just like any other types of disease, cancer tissue usually shows regional heterogeneity in cell preservation and cell type.