Application of Tissue Microarrays in Genomic Research

Application of Tissue Microarrays in Genomic Research

Many current literatures have demonstrated TMAs using paraffin medium and FFPE blocks for most studies due to the ease of specimen availability, long term storage, and cost-effectiveness for specimens. The TMA platform is an unparalleled tool to optimize assay and adapt novel molecular assays to archival paraffin tissues which are still a large and relatively untapped molecular repository. The remarkable value of TMA applications has been the efficiency and accuracy in the detection of clinicopathologic associations in a wide variety of diseases. The portability of this technique has also played a vital role in the widespread use of it and will continue to drive TMA applications.  

DNA / RNA Extraction & Quality Control

DNA / RNA Extraction & Quality Control

DNA and RNA extraction has played important and crucial roles in helping researchers and scientists to manipulate molecular biology analysis to have a better understanding in the biology of the earth. Due to the rapid advancement of technology, DNA and RNA extraction has improved vastly however, weaknesses of the instruments should be bettered constantly by conducting quality control as it affects all subsequent results.

FFPE Tissue Block Uses

FFPE Tissue Block Uses

FFPE is a great commodity to the research and medical field as it is an inexpensive and easy way to store and archive tissue specimens. It also preserves the integrity of the specimen for a long time and can therefore be used retrospectively in many studies which reduces the time needed to track down specific tissues that fit the criteria of the study.